Survival rates of mice in each treatment group inoculated with 1×108 cfu V. vulnificus.

The 96-h survival rate of the cefotaxime-plus-ciprofloxacin group (85%, 17/20) was significantly higher than that of the cefotaxime (0%, 0/20) or the cefotaxime-plus-minocycline groups (35%, 7/20) (P<0.001 and P = 0.003, respectively; log-rank test).