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posted on 2013-12-27, 03:32 authored by David N. Juurlink, Colin R. Dormuth, Anjie Huang, Chelsea Hellings, J. Michael Paterson, Colette Raymond, Anita Kozyrskyj, Yola Moride, Erin M. Macdonald, Muhammad M. Mamdani

The observation period for each patient begins with initiation of a proton pump inhibitor (PPI) and continues for 12 weeks. All patients were admitted to hospital for an acute myocardial infarction or heart failure at some point during the 12-week observation period, which for analytical purposes is divided into three identical 4-week intervals. The first of these is the risk interval, and the final interval defined the control interval.

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