Stability of mutated transcripts in xenografts.

<p>The prevalence of a glutamine to stop codon mutation at the 861 amino acid position of <i>APC</i> (APC:Q861*) and a glutamate to lysine mutation at 51 amino acid position of <i>TCF7L2</i> were evaluated on the forward and reverse transcripts from the parental human tumors (gray rows) and first and second generation xenografts (white rows) of D61540 and P2726, respectively.</p>