(A) The scatter plot shows the spine volume in mice treated with placebo (n = 207 spines from 9 dendrites, 3 dendrites per each of 3 mice) or fluoxetine (n = 175 spines from 9 dendrites, 3 dendrites per each of 3 mice). (B, C) Mean values of spine volume for all spines (Mann-Whitney U-test: U = 15930, p = 0.0425) (B) and spine density (Mann-Whitney U-test: U = 28, p = 0.2973) (C) in the placebo- or fluoxetine-treated mice. *p < 0.05 compared with the placebo-treated mice.