Spine morphology of CA1 basal dendrites.

<p>(A) Graphical representation of spine density/30μm of basal dendrites in the CA1 subarea; (B) Representative images of DIL dye staining of basal dendrites of the CA1 subarea (scale bar = 20 μm); (C) Graphical representation of the percentage of branched, thin, mushroom and stubby spines per total spines of basal dendrites of the CA1 subarea; Spine density and mushroom spines were increased in the trained group in the CA1 apical and basal dendrites; (D) Negative Spearman Correlation of spine density/30μm of basal dendrites of CA1 subarea with working memory error (WME) (r = -0.74, p = 0.04; r ranges from -1 to 0 to +1 where, -1 = 100% negative correlation, 0 = no correlation and +1 = 100% positive correlation). Statistical evaluation was carried out by multi-comparison one-way ANOVA followed by post-hoc Bonferroni's test. Data is provided as mean±SD (*P < 0.05;**P ≤ 0.01 ***P < 0.001; ****P < 0.0001)].</p>