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Serum hemolytic activity is increased in SSc patients.

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posted on 2015-02-06, 05:16 authored by Cinzia Scambi, Sara Ugolini, T. Sakari Jokiranta, Lucia De Franceschi, Oscar Bortolami, Valentina La Verde, Patrizia Guarini, Paola Caramaschi, Viviana Ravagnani, Guido Martignoni, Chiara Colato, Serena Pedron, Fabio Benedetti, Marco Sorio, Fabio Poli, Domenico Biasi

Sera from three different SSc patients (SSc1-SSc3) and three different healthy subjects (H1–H3) were tested both in the presence and absence of Mg-EGTA. Mg-EGTA was used to block the classical and lectin pathways of complement. Data are expressed as percentage of full RBC lysis.

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