Figure_4.tif (2.67 MB)
Sequence alignment of LCK, HCK, c-SRC, JAK1, JAK2 and JAK3 kinase domains.
figure
posted on 2014-09-08, 03:17 authored by Yankun Duan, Lin Chen, Yongheng Chen, Xue-gong FanThe conserved DFG motif is highlighted in blue box; the gatekeeper residue is highlighted in red box; residue corresponding to Met341 in c-Src is highlighted in purple box; several extra stretches of amino acids are highlighted in green box.
