Scatter plot showing no correlation between the percentage identity between the human (Homo sapiens) or Brugia malayi proteins that do or do not complement the essential functions of the yeast (Saccharomyces cerevisiae) orthologues.

The average protein identity (in %) between heterologous proteins able to complement the yeast deletions was 52.5 ± 10.6, whereas the identity between heterologous proteins NOT able to complement the yeast deletions was 48.1 ± 10.0.