Figure_2.tif (431.32 kB)
SNP rs2180341 per-allele hazard ratios (HRs) and 95% confidence intervals (CIs) among Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) in A. BRCA1 mutation carriers B. BRCA2 mutation carriers.
figure
posted on 2012-06-29, 01:24 authored by Tomas Kirchhoff, Mia M. Gaudet, Antonis C. Antoniou, Lesley McGuffog, Manjeet K. Humphreys, Alison M. Dunning, Stig E. Bojesen, Børge G. Nordestgaard, Henrik Flyger, Daehee Kang, Keun-Young Yoo, Dong-Young Noh, Sei-Hyun Ahn, Thilo Dörk, Peter Schürmann, Johann H. Karstens, Peter Hillemanns, Fergus J. Couch, Janet Olson, Celine Vachon, Xianshu Wang, Angela Cox, Ian Brock, Graeme Elliott, Malcolm W.R. Reed, Barbara Burwinkel, Alfons Meindl, Hiltrud Brauch, Ute Hamann, Yon-Dschun Ko, Annegien Broeks, Marjanka K. Schmidt, Laura J. Van ‘t Veer, Linde M. Braaf, Nichola Johnson, Olivia Fletcher, Lorna Gibson, Julian Peto, Clare Turnbull, Sheila Seal, Anthony Renwick, Nazneen Rahman, Pei-Ei Wu, Jyh-Cherng Yu, Chia-Ni Hsiung, Chen-Yang Shen, Melissa C. Southey, John L. Hopper, Fleur Hammet, Thijs Van Dorpe, Anne-Sophie Dieudonne, Sigrid Hatse, Diether Lambrechts, Irene L. Andrulis, Natalia Bogdanova, Natalia Antonenkova, Juri I. Rogov, Daria Prokofieva, Marina Bermisheva, Elza Khusnutdinova, Christi J. van Asperen, Robert A.E.M. Tollenaar, Maartje J. Hooning, Peter Devilee, Sara Margolin, Annika Lindblom, Roger L. Milne, José Ignacio Arias, M. Pilar Zamora, Javier Benitez, Gianluca Severi, Laura Baglietto, Graham G. Giles, kConFab, AOCS Study Group, Amanda B. Spurdle, Jonathan Beesley, Xiaoqing Chen, Helene Holland, Sue Healey, Shan Wang-Gohrke, Jenny Chang-Claude, Arto Mannermaa, Veli-Matti Kosma, Jaana Kauppinen, Vesa Kataja, Bjarni A. Agnarsson, Maria A. Caligo, Andrew K. Godwin, Heli Nevanlinna, Tuomas Heikkinen, Zachary Fredericksen, Noralane Lindor, Katherine L. Nathanson, Susan M. Domchek, SWE-BRCA, Niklas Loman, Per Karlsson, Marie Stenmark Askmalm, Beatrice Melin, Anna von Wachenfeldt, HEBON, Frans B. L. Hogervorst, Martijn Verheus, Matti A. Rookus, Caroline Seynaeve, Rogier A. Oldenburg, Marjolijn J. Ligtenberg, Margreet G.E.M. Ausems, Cora M. Aalfs, Hans J.P. Gille, Juul T. Wijnen, Encarna B. Gómez García, EMBRACE, Susan Peock, Margaret Cook, Clare T. Oliver, Debra Frost, Craig Luccarini, Gabriella Pichert, Rosemarie Davidson, Carol Chu, Diana Eccles, Kai-Ren Ong, Jackie Cook, Fiona Douglas, Shirley Hodgson, D. Gareth Evans, Rosalind Eeles, Bert Gold, Paul D.P. Pharoah, Kenneth Offit, Georgia Chenevix-Trench, Douglas F. EastonStudies are weighted and ranked according to the inverse of the between-study and within study variation of the log odds ratio, which is also represented by the size of the shaded box around the study-specific point estimate. The solid line indicates the OR = 1 and the dashed lined indicates the summary OR of all studies. A description of the study acronyms can be found in Supporting Information S1.
