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Rm155LG/Alb-Cre mice improved lipid metabolism in liver.

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posted on 2015-03-23, 03:00 authored by Xiaolin Lin, Junshuang Jia, Tao Du, Wei Li, Xiaoyan Wang, Jieqiong Wei, Xia Lin, Hui Zeng, Longping Yao, Xuebing Chen, Jingshen Zhuang, Jie Weng, Yu Liu, Jihong Lin, Qinghong Wu, Wanshan Wang, Kaitai Yao, Kang Xu, Dong Xiao

(A) Body weight of Rm155LG/Alb-Cre mice and controls at different ages. (B) Relative liver weight of Rm155LG/Alb-Cre mice vs. controls. (C) Adult Rm155LG/Alb-Cre mouse (right) and control (left) fed a normal diet. (D) Gross morphology of Rm155LG/Alb-Cre mouse (right) and control (left) livers. (E) H&E staining and Oil red O (ORO) staining of liver sections from control and Rm155LG/Alb-Cre mice. (F) Quantification of TC, TG, HDL and FFA storage in the liver of control and Rm155LG/Alb-Cre mice. TC, total cholesterols; TG, triglycerides; HDL, high-density lipoprotein; FFA, free fatty acids. Data are mean±SD (n = 9–10). Statistical significance was determined by two-tailed student t-test.

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