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Renal Histological Assessment

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posted on 2013-02-22, 09:20 authored by Anne E Bygrave, Kirsten L Rose, Josefina Cortes-Hernandez, Joanna Warren, Robert J Rigby, H. Terence Cook, Mark J Walport, Timothy J Vyse, Marina Botto

C57BL/6 mice, C57BL/6.Apcs−/− mice, and C57BL/6.129(D1Mit105–223) congenic mice were sacrificed at 1 y of age to obtain age-matched autopsy specimens. Bouin's fixed kidney sections were scored blinded for glomerulonephritis. Glomerulonephritis was graded on a 0–3 scale (see Materials and Methods for details).

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