Relevant characteristics of <i>S. pneumoniae</i> isolates and their prophages analyzed in this study.

a<p>Clones are named by their clonal complex number. Those showed in boldface and underlined are the main clones involved in Fq resistance in Spain since 2002.</p>b<p>Isolates are separated on the basis of their Fq susceptibility: S, susceptible (CPX MICs ≤2 mg/L); R, resistant (MICs ≥4 mg/L).</p>c<p>PCR detection for <i>hol1</i> gene.</p>d<p>Functional phages caused cell lysis in the presence of MitC.</p>