Relevant characteristics of S. pneumoniae isolates and their prophages analyzed in this study.

a

Clones are named by their clonal complex number. Those showed in boldface and underlined are the main clones involved in Fq resistance in Spain since 2002.

b

Isolates are separated on the basis of their Fq susceptibility: S, susceptible (CPX MICs ≤2 mg/L); R, resistant (MICs ≥4 mg/L).

c

PCR detection for hol1 gene.

d

Functional phages caused cell lysis in the presence of MitC.