Fig_6.tif (1.19 MB)
RTPCR of angiotensin receptor expression.
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posted on 2015-10-27, 03:50 authored by Harry A. Quigley, Ian F. Pitha, Derek S. Welsbie, Cathy Nguyen, Matthew R. Steinhart, Thao D. Nguyen, Mary Ellen Pease, Ericka N. Oglesby, Cynthia A. Berlinicke, Katherine L. Mitchell, Jessica Kim, Joan J. Jefferys, Elizabeth C. KimballGraph plots the relative expression of five tissues tested for the presence of AT1a, AT1b, and AT2 receptors- kidney, adrenal gland, retina, sclera and optic nerve from a CD1 mouse. To help normalize the results, a value was calculated by dividing the GAPDH primer treated tissue value by the mean quantification cycle (Cq) value for AT1A, AT1B, or AT2 primer tissue (relative expression). A lower value than 1 indicates a lower value for that receptor in tissue compared to GAPDH.
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IOP.ConclusionsThe neuroprotective effecttail cuff devicetranscription polymerase chain reactionRGC lossangiotensin receptors3 day IOP elevationscontrol glaucoma eyesscleral thicknessregression model penalaprilblood pressureExperimental Glaucoma PurposeToAlters Scleral RemodelingCD 1 miceLosartan Treatment Protects Retinal Ganglion Cellslosartan treatment decreasesAxonal transport blockade
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