posted on 2013-04-22, 02:02authored byRalf Duerrwald, Michael Schlegel, Katja Bauer, Théophile Vissiennon, Peter Wutzler, Michaela Schmidtke
Dyspnoea (A), rectal temperatures (B), virus titres in nasal swabs, n = 10 animals/group/day until day 2 p.i. and n = 5 from day 3 p.i. on, exception: n = 12 untreated animals at day 0 to 2 p.i. and n = 7 untreated animals/day at 3 to 7 p.i. (C), and mean of histopathological scores with standard deviations and representative photographs of formalin fixed, HE stained lungs (D) are shown (am morning; pm afternoon; p statistical probability: *p<0.05, **p<0.01, ***p<0.001, a vaccinated group versus control group, b Tamiflu®-treated group versus control group, c vaccinated group versus Tamiflu®-treated group, Mann-Whitney-U-test). The detection limit of virus titre determination is shown as dotted line (C).