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Proliferation and cell death in −DMSO and +DMSO HepaRG-AMC-BALs.

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posted on 2013-02-20, 03:45 authored by Geert A. A. Nibourg, Robert A. F. M. Chamuleau, Tessa V. van der Hoeven, Martinus A. W. Maas, An F. C. Ruiter, Wouter H. Lamers, Ronald P. J. Oude Elferink, Thomas M. van Gulik, Ruurdtje Hoekstra

Proliferation and cell death in the BALs was measured by their total DNA content (A), and leakage of AST (B) and LDH (C). AST and LDH leakage are expressed ‘per BAL’ (white bars; read along the left y-axis) and ‘per mg of DNA’ (grey bars; read along the right y-axis). Values are expressed as means ± standard deviations (n = 3 to 6). Significance: * P<0.05 versus pre-BAL suspensions (A) or −DMSO BALs (B, C).

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