Proliferation analysis of sarcoma cells.

<p>Chemical structures of A) costunolide and B) dehydrocostus lactone. STS cells were seeded at 10,000 per well and measured with the xCELLigence system. Dynamic proliferation curves for C) SW-872, D) SW-982, and E) TE-671 sarcoma cells in the presence of 0 (black triangles), 3 µg/ml (dark green circles), and 10 µg/ml costunolide (light green circles), or 3 µg/ml (yellow squares), and 10 µg/ml (red squares) dehydrocostus lactone. Both substances inhibited cell growth in a concentration dependent manner.</p>