Proliferation analysis of sarcoma cells.

Chemical structures of A) costunolide and B) dehydrocostus lactone. STS cells were seeded at 10,000 per well and measured with the xCELLigence system. Dynamic proliferation curves for C) SW-872, D) SW-982, and E) TE-671 sarcoma cells in the presence of 0 (black triangles), 3 µg/ml (dark green circles), and 10 µg/ml costunolide (light green circles), or 3 µg/ml (yellow squares), and 10 µg/ml (red squares) dehydrocostus lactone. Both substances inhibited cell growth in a concentration dependent manner.