Principal component analysis (PCA) score plots of isotopic abundance of plasma metabolites measured by isotope ratio mass spectrometers (i.e. glucose, palmitic, oleic, stearic, linolenic and arachidonic acids) between ZDF (<i>fa/+</i>) and ZDF (<i>fa/fa</i>) rats.

<p>Red dots are for ZDF (<i>fa/+</i>) whereas green ones stand for ZDF (<i>fa/fa</i>) rats. Letters are the identification code of the rat. Based on the PCA, there is a clear separation of both groups along PC1 and PC3, confirming that there is an isotopic signature at natural abundance that separates ZDF (<i>fa/+</i>) and ZDF (<i>fa/fa</i>) rats.</p>