Fig_3.tif (424.6 kB)
Pre-existing HBoV2 IgG reduces immune response against HBoV1 infection.
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posted on 2015-09-29, 04:10 authored by Kalle Kantola, Lea Hedman, Laura Tanner, Ville Simell, Marjaana Mäkinen, Juulia Partanen, Mohammadreza Sadeghi, Riitta Veijola, Mikael Knip, Jorma Ilonen, Heikki Hyöty, Jorma Toppari, Olli Simell, Klaus Hedman, Maria Söderlund-VenermoTwo illustrative cases of PCR-verified HBoV1 infections without (child #53) or with (child #122) pre-existing HBoV2 IgG are shown. The red, blue and black data points respectively indicate whether the serum tested positive by PCR, tested negative by PCR, or was not tested by PCR. The red open circle indicates a sample that was positive for HBoV1 IgM. Although not shown in the graphs, both children tested negative for HBoV3- and 4-specific IgG.
