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Pre-existing HBoV1 IgG reduces immune response against HBoV2 infection.
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posted on 2015-09-29, 04:10 authored by Kalle Kantola, Lea Hedman, Laura Tanner, Ville Simell, Marjaana Mäkinen, Juulia Partanen, Mohammadreza Sadeghi, Riitta Veijola, Mikael Knip, Jorma Ilonen, Heikki Hyöty, Jorma Toppari, Olli Simell, Klaus Hedman, Maria Söderlund-VenermoTwo representative cases of PCR-verified HBoV2 infections without (child #52) or with (child #108) pre-existing HBoV1 IgG are shown. The red, blue and black data points respectively indicate whether the serum tested positive by PCR, tested negative by PCR, or was not tested by PCR. Although not shown in the graphs, both children tested negative for HBoV3- and 4-specific IgG.
