Perceptual bias is reduced in patients with MDD with diminished depressive symptoms.

<p>MDD = major depressive disorder; HC = healthy controls. Bar plots depicting mean PSEs <b>(A)</b> and slopes <b>(B)</b> of the logistic functions for the two groups and two time points. A significant interaction of time and group was observed for the PSE, indicating the inflection point of the logistic functions (p < 0.001). For the slopes of the logistic functions, indicating the abruptness of the categorical shift from sad to happy, no main effects or interactions were found. *: interaction of time and group, p < 0.001. Error bars denote within-subject standard errors of mean [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0129863#pone.0129863.ref053" target="_blank">53</a>].</p>