posted on 2013-02-20, 09:34authored byMasamitsu Shimazawa, Yasushi Ito, Yuta Inokuchi, Hajime Yamanaka, Tomohiro Nakanishi, Takuya Hayashi, Bin Ji, Makoto Higuchi, Tetsuya Suhara, Kazuyuki Imamura, Makoto Araie, Yasuyoshi Watanabe, Hirotaka Onoe, Hideaki Hara
LGN: lateral geniculate layer, ONH: optic nerve head, ON: optic nerve, GFAP: glial fibrillary acidic protein, Iba-1: ionized calcium-binding adaptermolecule-1, PBR: peripheral benzodiazepine receptor. Glaucoma stages were classified by histological changes based on the extent of axonal loss as mild (0–20%), moderate (20–50%), and advanced glaucoma (50–100%). Neuronal atrophy, RGC loss and immunoreactivity were classified based on the quantitative data as follows: no changes; −, mild; +, moderate; ++, robust; +++.