Passive immunization with 9GlcNH<sub>2</sub>-Hla antibodies in a murine model of <i>S. aureus</i> pneumonia.

<p>(a) Mice were vaccinated i.n with 20 µl of 9GlcNH<sub>2</sub>-Hla antisera or NRS 24 h and 4 h prior to infection with indicated <i>S. aureus</i> strains (4×10<sup>8</sup> CFU/mouse). Bacterial burden was recorded 24 h post-infection. Points indicate cfu/lung of individual mice, lines the group median; p values: Mann-Whitney test. (b) Kaplan–Meier survival curve of 4 week old FVB mice vaccinated i.n with 20 µl of 9GlcNH<sub>2</sub>-Hla antisera or NRS 24 h and 4 h prior to infection with indicated <i>S. aureus</i> strains (6×10<sup>8</sup> CFU/mouse). Survival was monitored at least twice a day over a 5 day period and data analyzed using the Log-rank test to derive the p values.</p>