Partial CLUSTAL 2.1 multiple sequence alignment of publicly available <i>Brugia malayi</i> (Bm1_48165), <i>Homo sapiens</i> (<i>Hs</i>SAH), <i>Saccharomyces cerevisiae</i> (<i>Sc</i>SAH), and our cloned <i>Brugia malayi</i> (<i>Bm</i>SAH) S-adenosyl homocysteinases, showing the “insert” missing from the publicly available nematode protein sequence.

<p>The absence of the 27 amino acids in the publicly available <i>Brugia</i> sequence (Bm1_48165) could indicate a splice variant of the enzyme or simply a problem with the genome assembly.</p>