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Parasite Susceptibility to Glucantime in the THP1 Cell Line

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posted on 2013-02-22, 08:44 authored by Ramtin Hadighi, Mehdi Mohebali, Patrick Boucher, Homa Hajjaran, Ali Khamesipour, Marc Ouellette

Parasites expressing the firefly luciferase were used to infect THP1, and the levels of parasites surviving Glucantime treatment were calculated by measuring luciferase activity expressed as percentage relative light unit (RLU %). The average of two independent experiments performed in duplicate is shown. Open circles indicate strain 175 (sensitive); open triangles indicate strain 467 (intermediate resistance); and open squares indicate strain 827 (high resistance).

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