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PAR2-AP-induced mucus secretion in mice.

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posted on 2013-02-20, 00:52 authored by Hyun Jae Lee, Yu-Mi Yang, Kyubo Kim, Dong Min Shin, Joo-Heon Yoon, Hyung-Ju Cho, Jae Young Choi

(A) Images of mucus bubbles in the tracheas of wild type littermates, PAR-2 knock out and targeted ΔF508 CFTR mutant mice 10 min after PAR2-AP stimulation. Scale bar: 0.5 mm. (B) Secretion rates in response to PAR2-AP (100 µM) or carbachol (10 µM) in mouse tracheal glands. Data represent mean ± S.E.M. secretion rates from four to eight mice.

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