Fig_1.tif (601.04 kB)
Overview of immunomagnetic reduction (IMR).
figure
posted on 2015-09-18, 03:31 authored by Bing-Hsien Liu, Yu-Chen Lin, Chia-Shin Ho, Che-Chuan Yang, Yun-Tsui Chang, Jui-Feng Chang, Chun-Yuan Li, Cheng-Shun Cheng, Jiun-Yan Huang, Yen-Fu Lee, Ming-Hung Hsu, Feng-Chun Lin, Hao-Ching Wang, Chu-Fang Lo, Shieh-Yueh Yang, Han-Ching Wang(A) Each magnetic nanoparticle, bio-functionalized with antibodies against target proteins, oscillates with the applied alternating current (AC) magnetic field before binding with ICP11. χac,0: the original multiple-frequency AC magnetic susceptibility of the magnetic nanoparticles (B) When these magnetic nanoparticles bind to target proteins, they become larger, and some even form clusters. This reduces the AC magnetic susceptibility of the reagent. χac,ϕ: the resulting magnetic susceptibility of magnetic nanoparticles after binding with the target proteins.
