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Observed glycosylation and fully-glycosylated model of HCMV gB.

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posted on 2015-10-20, 03:17 authored by Heidi G. Burke, Ekaterina E. Heldwein

(A) HCMV gB is shown in surface representation in wheat. Glycans observed in the structure are shown in space-filled representation in teal. Residues shown to be important for antibody binding are colored as in Fig 6. (B) To obtain a glycosylation model representative of mammalian glycosylation, high-mannose type glycans (Man8-GlcNAc2-N-Asn) were modeled onto the structure of gB. Paucimannose and high-mannose are shown schematically.

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