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Numbers and areas of GST-P+ foci in the livers of rats treated with DEN or vehicle and administered Valerian at doses of 50, 500 and 5000 ppm.

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posted on 2014-11-24, 03:31 authored by Anna Kakehashi, Ayumi Kato, Naomi Ishii, Min Wei, Keiichirou Morimura, Shoji Fukushima, Hideki Wanibuchi

Data are Mean ± SD (all survived rats were subjected to analysis). **P<0.01; ***P<0.0001 versus the DEN control group.

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    PLOS ONE

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    DEN control ratscyclin D 1p 21Waf p 53rat liver bioassayhepatocarcinogenesigabaMale F 344 ratsBax mRNA expressionCell proliferationValerian Inhibits Rat HepatocarcinogenesisfocicypDEN initiation control rats7aoxidative DNA damagecell cycle progression

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