Fig_5.tif (1.82 MB)
Nicotinamide reduced arsenic and UV-induced 8oxoG levels in the epidermal layer of ex vivo human skin at 45 minutes after UV irradiation (a).
figure
posted on 2015-02-06, 02:47 authored by Benjamin C. Thompson, Gary M. Halliday, Diona L. DamianSamples were exposed to either 50μM nicotinamide, 2μM sodium arsenite, PBS (control) with or without 2J/cm2 of UV. The columns represent the mean ±SEM (n = 3). * = p<0.05, ** = p<0.01 one way ANOVA. Staining of 8oxoG 45 minutes following UV radiation, arsenic and nicotinamide exposure in ex-vivo human skin (b). The blue staining represents DAPI (nuclear staining). The red staining represents 8oxoG staining.