Nerve fibers in cross sections of the distal colon.

Orderly distribution of fibers labelled by neuron specific anti-β-tubulin (III) antibody was observed in colon sections from sham-treated guinea-pigs at all time points (A-A^II). Disorganized, fragmented, and irregularly dispersed fibers were evident within the mucosa of sections from TNBS-only (B-B^II) and UCM-treated (E-E^II) animals at all time points. Damage to nerve fibers was present in sections from MSC and CM-treated animals at 6 hours (C-D), however re-growth of nerve fibers was observed at 24 (C^I-D^I) and 72 hours (C^II-D^II). n = 4/group/time point. Scale bars = 50μm.