Multivariate linear regression models to investigate associations between beneficial responses, entropy, HLA alleles and % inhibition (dependent variable).
posted on 2015-02-27, 03:57authored byGemma Hancock, Hongbing Yang, Elisabeth Yorke, Emma Wainwright, Victoria Bourne, Alyse Frisbee, Tamika L. Payne, Mark Berrong, Guido Ferrari, Denis Chopera, Tomas Hanke, Beatriz Mothe, Christian Brander, M. Juliana McElrath, Andrew McMichael, Nilu Goonetilleke, Georgia D. Tomaras, Nicole Frahm, Lucy Dorrell
In each model, magnitude = total beneficial response (sum of responses to beneficial peptide pools)
Ratio of protective / total response = total beneficial response / total proteome response (both defined as IFN-γ+ cells/million CD8+ T cells)
* HLA-B*27, B*51, B*5701, B*5801, B*81
§ HLA-B*35 (Py), HLA-B*53
Multivariate linear regression models to investigate associations between beneficial responses, entropy, HLA alleles and % inhibition (dependent variable).