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Modafinil treatment prevents METH-induced increase of pro-apoptotic and decrease of anti-apoptotic markers in the striatum.
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posted on 2013-02-19, 22:15 authored by Mariana Raineri, Betina Gonzalez, Belen Goitia, Edgar Garcia-Rill, Irina N. Krasnova, Jean Lud Cadet, Francisco J. Urbano, Veronica BisagnoExpression of pro-apoptotic BAX (A) and anti-apoptotic Bcl2 (B) proteins in the striatum, measured by Western blot analyses. Striata were obtained 16 hours after VEH, MOD, METH or M+M treatments (n = 5−9).Values represent mean ± SEM (% of control). One-way ANOVA followed by Fisher’s LSD. different letters: p<0.05.
