Figure_3.tif (4.93 MB)
MetaMapp visualization of metabolic changes in stem cells relative to m15 fibroblast cells.
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posted on 2012-10-15, 02:22 authored by John K. Meissen, Benjamin T. K. Yuen, Tobias Kind, John W. Riggs, Dinesh K. Barupal, Paul S. Knoepfler, Oliver FiehnRed nodes represent metabolites with increased signal intensity in stem cells; blue nodes represent metabolites with decreased signal intensity in stem cells (p<0.05). White nodes represent detected metabolites without statistically significant changes. Node sizes scale with fold change. Blue edges connect metabolites with Tanimoto chemical similarity >700; red edges connect reaction-pair metabolites from the KEGG RPAIR database. (A): MetaMapp network comparing mESCs to m15 fibroblasts. (B): MetaMapp network comparing mESCs to m15 fibroblasts.