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Median age at DCM onset by SPP1 and LTBP4 genotype.

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posted on 2015-10-29, 03:54 authored by Andrea Barp, Luca Bello, Luisa Politano, Paola Melacini, Chiara Calore, Angela Polo, Sara Vianello, Gianni Sorarù, Claudio Semplicini, Boris Pantic, Antonella Taglia, Ester Picillo, Francesca Magri, Ksenija Gorni, Sonia Messina, Gian Luca Vita, Giuseppe Vita, Giacomo P. Comi, Mario Ermani, Vincenzo Calvo, Corrado Angelini, Eric P. Hoffman, Elena Pegoraro

*Significant difference between genotypes (log-rank p<0.05).

§DCM onset was observed in less than 50% of patients, so no median value can be calculated.

Total n for LTBP4 differs due to limited DNA availability in a few patients. For SPP1, patients included in the previous report about loss of ambulation (Pegoraro et al, 2011) were also excluded. SPP1: Secreted PhosphoProtein 1. LTBP4: latent transforming growth factor beta binding protein 4. DCM: dilated cardiomyopathy.

Median age at DCM onset by SPP1 and LTBP4 genotype.

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