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MS-275 enhances expression of acetyl-histone H3 in obstructed kidneys.

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posted on 2013-01-16, 01:58 authored by Na Liu, Song He, Li Ma, Murugavel Ponnusamy, Jinhua Tang, Evelyn Tolbert, George Bayliss, Ting C. Zhao, Haidong Yan, Shougang Zhuang

Kidney tissue lysates were subject to immunoblot analysis with specific antibodies against acetyl-histone H3 (A). Expression levels of acetyl-histone H3 and histone H3 were quantified by densitometry and normalized with histone H3 (B) and GAPDH, respectively (C). Data are represented as the mean ± SEM (n = 6). Means with different superscript letters are significantly different from one another (P<0.05). Photomicrographs illustrate acetyl-histone H3 with immunofluorescent staining after various treatments as indicated (D).

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