MCPG blocks TBS-induced shifts in E_GABA in both juvenile and neonatal rat hippocampal neurons.

MCPG (500 μM) was applied into superfusion medium 10 min prior to TBS conditioning. In panels A & B, the effects of MCPG on the TBS-induced shifts in E_GABA are shown from 9–12 and 3–5 day old rat hippocampal neurons, respectively. Data were obtained from two different CA1 neurons and holding potential for each individual cell was -60 mV. Note that MCPG blocked TBS-induced negative shift in E_GABA in both juvenile and neonatal rat hippocampal neurons. The whole-cell recording method was used.