Figure_1.tif (122.47 kB)
MAML1 enhances the transcriptional activity of Runx2.
figure
posted on 2013-02-19, 17:14 authored by Takashi Watanabe, Toshinao Oyama, Maki Asada, Daisuke Harada, Yoshiaki Ito, Masayo Inagawa, Yutaka Suzuki, Sumio Sugano, Ken-ichi Katsube, Gerard Karsenty, Toshihisa Komori, Motoo Kitagawa, Hiroshi AsaharaA, 293T cells were transiently transfected with p6OSE2-Luc reporter, Runx2 expression plasmid, and about 10,000 FLJ expression plasmids. B, 293T cells were transiently transfected with a p6OSE2-Luc reporter or p6OSE2-mutant-Luc together with MAML1, MAML2, MAML3, and Runx2 expression plasmids. Luciferase levels were normalized to the Renilla luciferase activity of a cotransfected phRL-TK-Luc reporter and presented as fold activation relative to the luciferase level of the p6OSE2-Luc reporter construct alone. Error bars represent the standard deviation of triplicate transfections.
