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Lung inflammation during endotoxemia.

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posted on 2013-02-20, 03:07 authored by Adrián González-López, Alina Aguirre, Inés López-Alonso, Laura Amado, Aurora Astudillo, María Soledad Fernández-García, María F. Suárez, Estefanía Batalla-Solís, Enrique Colado, Guillermo M. Albaiceta

N = 7/group. LPS injection increases histological damage (A-B) and neutrophilic infiltration (C-E). Mice lacking MMP-8 show a more severe injury with increased neutrophils within the lung tissue (C-D) and bronchalveolar lavage fluid (N = 4/group, E). However, there were no differences in survival (F, n = 9 per genotype, log rank test p = 0.52). *p<0.05 in post-hoc tests.

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