Loss of <i>Hnf1α</i> leads to deregulation of enteroendocrine cell production.

<p>(A) Chromogranin A immunodetection was performed on ileum tissue sections. Representative micrographs and statistical analyses of the number of positive labeled-cells per crypt-villus axis. n = 3-4; average of 40 crypt-villus axis per mouse. (B) qRT-PCR analysis performed on total RNA extracts from 4-month-old mice (means +/- SEM). n = 5-10. *<i>P</i><0.05; **<i>P</i><0.01; ***<i>P</i><0.001.</p>