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Liver and lymph node pathological changes related to Hg presence.

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posted on 2013-02-20, 18:21 authored by Sandro Mazzariol, Giovanni Di Guardo, Antonio Petrella, Letizia Marsili, Cristina M. Fossi, Claudio Leonzio, Nicola Zizzo, Salvatrice Vizzini, Stefania Gaspari, Gianni Pavan, Michela Podestà, Fulvio Garibaldi, Margherita Ferrante, Chiara Copat, Donato Traversa, Federica Marcer, Sabina Airoldi, Alexandros Frantzis, Yara De Bernaldo Quirós, Bruno Cozzi, Antonio Fernández

Gross features, hematoxylin and eosin (HE) and automethallographic staining, along with ESEM pictures of liver (respectively, Fig. A–D; Fig. B and C have a 10× magnification) and lymph nodes (respectively, Fig. E–H; Fig. B and C have a 40× magnification). In HE-stained sections, hepatic macrovacuolar lipidosis in the liver and macrophages loaded with brownish pigments are evident. HgSe crystals can be observed in the liver (hepatocytes and Kuppfer cells) and lymph nodes (sinusal macrophages) both with the automethallographic staining (black arrows) and ESEM pictures (white arrows). In Fig. G also follicular lymphoid depletion is prominent (*).

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