LBP facilitated CIH-activated hippocampal regeneration through Akt/PCNA axis.

Levels of the protein expression (upper panel) of (A) BDNF (B) PTEN, (C) p-Akt, (D) p-JNK, (E) p-c Jun, (F) PCNA and (G) cyclin D1 in the hippocampus of the normoxic (Nx) or hypoxic (IH) groups; LBP-treated hypoxic (IH+LBP) or normoxic (Nx+LBP) groups are summarized. For BDNF, *p < 0.05 when compared with Nx groups, ^#p < 0.05 when compared with Nx+LBP groups, ^$p < 0.05 when compared with Nx groups, ^{^}p < 0.05 when compared with Nx +LBP groups. For PTEN, p-JNK, p-c Jun and cyclin D1, *p < 0.05 when compared with Nx, ^#p < 0.05 when compared with IH+LBP, ^$p < 0.05 when compared with Nx+LBP groups. For Akt and PCNA, *p < 0.05 when compared with Nx groups, ^#p < 0.05 when compared with IH+LBP groups P, ^$p < 0.05 when compared with Nx+LBP groups, ^{^}p < 0.05 when compared with Nx, ^!p < 0.05 when compared with Nx+LBP groups.