LBP ameliorated extrinsic caspase-dependent apoptosis induced by CIH treatment.

Levels of the protein expression (upper panel) of (A) TNFα, (B) FADD, (C) cleaved caspase 8 and (D) Bid in the hippocampus of the normoxic (Nx) or hypoxic (IH) groups; LBP-treated hypoxic (IH+LBP) or normoxic (Nx+LBP) groups are summarized. β-actin was an internal control. Data are mean ± SEM (n = 6–8). For TNFα, FADD and Bid, *p < 0.05 when compared with Nx, ^#p < 0.05 when compared with IH+LBP, ^$p < 0.05 when compared with Nx+LBP groups. For cleaved caspase 8, *p < 0.05 when compared with Nx, ^#p < 0.05 when compared with IH+LBP, ^$p < 0.05 when compared with Nx+LBP groups, ^{^}p < 0.05 when compared with Nx, ^!p < 0.05 when compared with Nx+LBP.