Knockdown of smyhc1 expression or hsp90α1 mutation resulted in defective thin filament organization in skeletal muscles of zebrafish embryos.

A–C. Anti-α−actin antibody staining shows the organization of thin filaments in slow muscles of control (A), smyhc1 knockdown (B), or slotu44c mutant (C) embryos at 48 hpf. D, F. Anti-α−actin antibody staining shows the organization of thin filaments in fast muscles of control (D), smyhc1 knockdown (E), or slotu44c mutant (F) embryos at 72 hpf. Scale bar = 25 µm in A.