Figure_7.tif (1.59 MB)
KCl stimulated Elk1 SUMOylation reduces endogenous katanin-p60 protein level in SH-SY5Y cells.
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posted on 2013-07-24, 06:19 authored by Ece Selçuk, Koray Kırımtay, Derya Canbaz, Güher Işık Cesur, Sirin Korulu, Arzu Karabay(A) Immunocytochemistry staining of endogenous katanin-p 80 to reveal the effect of KCl treatment on the Elk1 mediated expression of KATNB1 gene in SH-SY5Y cells. Control represents naive SH-SY5Y cells that were neither transfected nor KCl treated; Elk1 represents SH-SY5Y cells that were pCMV6-Elk1 transfected and finally Elk1+KCl represents SH-SY5Y cells that were both pCMV6-Elk1 transfected and KCl treated. Green indicates katanin-p80 staining, while blue is for nuclear DAPI staining. (B) Integrated pixel analysis for katanin-p80 expression in panel A.
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biophysicsCell motilitymicrotubulesgeneticsgene expressionDNA transcriptionMolecular geneticsGene regulationgenomicsGenome expression analysisMolecular cell biologySignal transductionSignaling in cellular processesTranscriptional signalingneurologydementiaAlzheimer diseasestimulatedelk1sumoylationendogenouskatanin-p60sh-sy5y
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