Fig_3.tif (277.04 kB)
Intracellular GSH levels and susceptibility to CdSe QD-induced cytotoxicity.
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posted on 2015-09-24, 03:07 authored by Wei Wang, Yan He, Guodong Yu, Baolong Li, Darren W. Sexton, Thomas Wileman, Alexandra A. Roberts, Chris J. Hamilton, Ruoxi Liu, Yimin Chao, Yujuan Shan, Yongping Bao(A) Effect of SFN on intracellular GSH levels. HHL-5 cells were exposed to SFN (2.5, 5 and 10 μM) with DMSO (0.1%) as a control for 0, 3, 6, 12 and 24 h. The levels of intracellular GSH were measured by an HPLC assay. Data are shown as means ± SEM (n = 3). (B) Effect of SFN and BSO pre-treatment on CdSe QD-induced cytotoxicity. HHL-5 cells were pre-treated with SFN (5 μM) and/or BSO (100 μM) for 24 h, and then incubated with 20 μM CdSe QDs for another 24 h. Cytotoxicity was measured by MTT assay, and data shown as means ± SD (n = 6). *P<0.05, **P<0.01.
