Figure_3.tif (263.66 kB)
Interferon signaling pathways was highly up-regulated in moderate and mild influenza patients but was attenuated in patients with severe outcome.
figure
posted on 2014-11-03, 03:32 authored by Long Truong Hoang, Thomas Tolfvenstam, Eng Eong Ooi, Chiea Chuen Khor, Ahmand Nazri Mohamed Naim, Eliza Xin Pei Ho, Swee Hoe Ong, Heiman F. Wertheim, Annette Fox, Chau Van Vinh Nguyen, Ngoc My Nghiem, Tuan Manh Ha, Anh Thi Ngoc Tran, Paul Tambayah, Raymond Lin, Chariya Sangsajja, Weerawat Manosuthi, Chareon Chuchottaworn, Piamlarp Sansayunh, Tawee Chotpitayasunondh, Piyarat Suntarattiwong, Kulkanya Chokephaibulkit, Pilaipan Puthavathana, Menno D. de Jong, Jeremy Farrar, H. Rogier van Doorn, Martin Lloyd HibberdUp-regulated genes were highlighted in grey. IFNGR1 was the only gene that was up-regulated in severe patients while a large number of other genes were up-regulated in moderate and mild patients.
