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Inhibition of the nuclease activity of LiEndoG by Lei49.

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posted on 2014-02-26, 04:13 authored by Eva Rico, Cristina Oliva, Kilian Jesús Gutierrez, Juan Fernando Alzate, Carlos Mario Genes, David Moreno, Elena Casanova, Alba Gigante, María-Jesús Pérez-Pérez, María-José Camarasa, Joachim Clos, Federico Gago, Antonio Jiménez-Ruiz

LiEndoG activity was assayed by the cleavage of a dually labeled double-stranded probe. DNA degradation is followed by the increase in fluorescence observed over 40 min of probe digestion in the presence of increasing amounts of Lei49.

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