Inhibition of anagen induction from telogen by 6-gingerol in C57BL/6 mice.

After depilation, the skin on the back was treated with vehicle (right) or 1 mg/ml 6-gingerol (left) every day for 10 days. Photographs of each animal were taken every 5 days. Compared to the vehicle-treated control, 1 mg/ml 6-gingerol can significantly inhibit anagen induction from telogen. (A) Day zero, (B) 5 days, (C) 10 days, (D) 15 days and (E) 20 days after depilation. (F) Enlarged photograph of the left-hand mouse in (E).