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Infection, dissemination and transmission rates in Cairns Ae. aegypti 14 days after exposure to 1997/98 and 2008/09 strains of dengue virus type 3, as determined using a cell culture-enzyme immunoassay and the monoclonal antibody, 4G2.

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posted on 2013-07-16, 03:21 authored by Scott A. Ritchie, Alyssa T. Pyke, Sonja Hall-Mendelin, Andrew Day, Christopher N. Mores, Rebecca C. Christofferson, Duane J. Gubler, Shannon N. Bennett, Andrew F. van den Hurk

See Materials and Methods section for details on conduct of the three trials.

a

Titer (log10CCID50/mL) of the infectious blood meal to which mosquitoes were exposed.

b

Percentage of mosquitoes containing virus in their bodies (number positive/number tested).

c

Percentage of mosquitoes containing virus in their legs and wings (number positive/number tested).

d

Percentage of mosquito expectorates in which virus was detected (number of positive expectorates/number tested).

e

P value calculated by Fisher’s Exact test.

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    Computational biologySequence analysisEvolutionary biologyEvolutionary systematicsphylogeneticsgenomicsGenome sequencingmicrobiologyVirologyViral transmission and infectionepidemiologyInfectious disease epidemiologyInfectious diseasesneglected tropical diseasesDengue feverViral diseasesdengueVectors and hostsmosquitoesdisseminationratescairns14daysstrainsculture-enzymeimmunoassaymonoclonal

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