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In vitro gluconeogenesis is suppressed by a RORα antagonist.

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posted on 2015-09-18, 03:47 authored by Hiroshi Matsuoka, Akiho Shima, Daisuke Kuramoto, Daisuke Kikumoto, Takashi Matsui, Akihiro Michihara

(A) Glucose production in HepG2 cells incubated for 4 h in 10 μM SR1001, a RORα antagonist, or in DMSO. (B) Effect of 10 μM SR1001 on PEPCK mRNA expression in HepG2 cultures 7 h after treatment. Data are mean ± S.E. of triplicate experiments. *, p < 0.05.

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